Protagonists from the main games: Red, Leaf, May, Brendan, Dawn, Lucas, Ethan, Lyra, Hildam, Hilbert, Calem and Serena.
I'll always be a Generation II fan so the release of Heart Gold and Soul Silver was pretty much the highlight of the franchise for me.
Edit: Finally added Generation V. Enjoy!
Edit: Added BW2 protagonists 8]
Edit: Added XY protagonists